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Description
The underlying cause of deficiency is the most important determinant
A typical pattern involves 4 to 6 weeks of daily administration followed by 2 to 4 weeks off

What McGuire and his colleagues found as they read through the literature was a decidedly mixed bag

He is truly exceptional
A: Activates GLP-1 receptors in the pancreas (glucose-dependent insulin secretion), hypothalamus (appetite regulation), and GI tract (delayed gastric emptying)

There's no established upper limit for B12, and toxicity is extremely rare
