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Further, it was revealed that the increased synaptic transmission was blocked by PI3k inhibitors, indicating that this effect is dependent on PI3k activation [9]

Thus, there were increased intraocular pressure and mydriasis, degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy in glaucomatous rats [11]

Among them, collagen-I fibrin is a strong fibrin subtype, accounting for about 95% of the total collagen in the extracellular matrix of normal tendons [49]

Zhen, W

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