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Comparison of the cytoprotective potential of chelator SIH and prochelator BSIH The comparison of diverse Fe chelators revealed that although some protection can be a general property of Fe chelators, the lipophilic agents (L1, ICL-670A, SIH) have higher potential to exert neuroprotection, apparently due to the better access to intracellular labile Fe pool

PDE1, PDE2, PDE3, PDE10 and PDE11 exhibiting dual specificity, for cAMP and cGMP, although with different affinities, depending on the isoform

Due to its important antioxidant role, it is widely used in medicine, as a food additive, and in the cosmetic industry

NPC1L1 may yet prove to be the putative intestinal cholesterol transporter

The detection of hundreds of unique-to-mushroom-variety compounds emphasizes the differences in chemical composition of these varieties of edible fungi

This allowed us to observe a higher mitochondrial mass and membrane potential in aged Mda5 -/- HSCs, a characteristic of young HSCs 47,48,49 , albeit in studies utilizing verapamil (Fig