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Description
ICAM-1, intercellular adhesion molecule-1
30 To date over 200 individual nucleotide changes which cause pathogenic mutations have been described (Figure 4, RettBASE
[PubMed: 7688729] 504
Failla, C., Tomei, L
The inability to adapt to the different cellular and environmental needs/stressors results in metabolic inflexibility, which ultimately leads to disease states like insulin resistance, lipid accumulation, and an inability to maintain homeostatic balance [2426] (Figure 6)
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