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Acetaminophen poisoning can be due to ingestion of a single overdose (usually as an attempt at self-harm) or ingestion of excessive repeated doses or too-frequent doses, with therapeutic intent
Stockwells group identified two chemicals, erastin and RSL3, which appear to selectively kill cancer cells with RAS mutations

J Microbiol Methods 127:188192

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Deconjugation As related to the mercapturate pathway, deconjugation is defined as the removal of the intact cysteine-containing moiety (usually as GSH) from the thioether conjugate (Stevens and Jones, 1989)
