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Washart '12 William Wassel, M.D
illustrate the feasibility of targeting BCAAs metabolism in GBM for tumor therapy (Fig
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If G binds to the T 5 helix of the TIM barrel-like domain, the same orientation effects could occur, but there may also be a significant allosteric component to activation because this helix contacts two autoinhibitory elements, the XY linker and H 2 helix (Fig
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HEPATOLOGY 2003
