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Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

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Stressful steps: progress and challenges in understanding stress-induced mRNA condensation and accumulation in stress granules

Alzheimers disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

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