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Karunanayake, A

lncRNAs can exert their roles through different mechanisms that can be summarized as described below (30)

Interestingly, a few years ago it has been published that in flies missense mutations of the SLC25A39 homologue shawn results in accumulation of ROS as well as in mitochondrial dysfunction, synaptic defects, and neurodegeneration

and transcription of interferon-stimulated genes

Instead of using TFA for deprotection, a solution of HCl in 1,4-Dioxan ( c = 4 M, 5 equiv) was used, whereas 3i could be obtained after purification by column chromatography as a hydrochloride salt in a yield of 61.3 mg (0.4 mmol, 80%)

Ann Rheum Dis (1997) 56(3):1803