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Aldehyde dehydrogenases: not just markers, but functional regulators of stem cells

This can lead to ferroptotic cell death through increased lipid peroxidation and accumulation of ROS (Wang et al., 2020)

The combination produces gradual softening of expression lines over several months of use

PMID: 37126209 Theriogenology2023 Jan 1:195:77-84

2.11 Reduced glutathione quantification GSH quantification was performed using established Ellman Assay, where GSH reacts specifically with the Ellmans reagent (DTNB) to yield 2-nitro-5-mercapto-benzoic acid (TNB), which produces a concentration-dependent yellow chromophore quantifiable by spectrophotometry (Vuolo et al., 2022)

Two endocannabinoids, anandamide and 2-arachidonoylglycerol, suppressed proliferation, induced apoptosis, deregulated the expression of cytoskeletal proteins (i.e., cytokeratins), upregulated lipid synthesis, and selectively activated the mitogen-activated protein kinase (MAPK) signaling pathway in human eccrine-sweat-gland-derived immortalized NCL-SG3 model cells