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"Nicotinamide N-methyltransferase (NNMT): a novel therapeutic target for metabolic syndrome." Frontiers in Pharmacology

Of the remaining 45 articles, 6 full texts could not be retrieved and 14 were excluded as they were out of scope

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Overview 5-Amino-1MQ is classified as a potent and selective NNMT inhibitor that appears to preserve both S-adenosylmethionine (SAM) and nicotinamide, potentially enhancing NAD+ availability and cellular energetics