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#CardsJC: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes - SELECT Trial

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Semaglutide significantly reduced LVH, improve mitophagy, and down-regulated NLRP3 inflammatory signal pathway in TAC rats

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Improves mitochondrial function and efficiency

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GLP-1 therapies lead to weight loss mainly from fat, but a portion includes muscle

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