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However, there will be out-of-pocket expenses for care, which can be costly if you travel from out of state and must include travel costs, lodging, and meals.

Similarly, the expression of multidrug resistance-associated protein 2 can reduce intracellular cisplatin levels by effluxing the drug, thereby diminishing its efficacy (60)

In FM patients, stimulation of target areas such as the primary motor cortex (M1) [59], dorsolateral prefrontal cortex (DLPFC) [62, 68] and operculo insular cortex (OIC) [66, 67] improves fatigue [69], quality of life (QoL) [69], pain catastrophizing and pain-related disability [68]

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(Prepared byTufts Medical Center Evidence-based Practice Center under Contract No.HHSA-290-07-10055.) Rockville, MD: Agency for Healthcare Research andQuality