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Moreover, in the skeletal muscles of AX-treated obese and lean mice, the expression levels of Sirtuins, such as Sirt1 and Sirt3, were upregulated (Figure 2)

Recent studies have shown that an increase in trans fats in the human diet may lead to an increase in levels of low-density lipoproteins (LDL), or bad cholesterol, which in turn may lead to plaque deposition in the arteries, resulting in heart disease

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