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Description
Most patients find the procedure tolerable and experience no significant pain
Apoptosis is the most commonly studied type of cell death in the cuprizone model as it is well understood and easy to assess
The compound also decreased the activity of stress-induced kinases (SAPK/JNK and pERK1/2), suggesting additional neuroprotective mechanisms beyond simple neurotrophin upregulation
More severe structural damage heals more slowly regardless of peptide use
HGF inhibitors Since HGF is the only known ligand of MET, formation of a HGF:MET complex blocks MET biological activity
The ETF was the last data point before rupture
