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A positive depolarized control was used, in which cells were previously incubated with 50 M CCCP for 5 min (37 C, 5% CO 2 ) and then incubated with JC-1

To address this knowledge gap, here we develop a mathematical model that incorporates the most essential molecular elements for NADPH production, ROS generation, GSH synthesis, and detoxification of ROS by GSH in the outer retina, formed by photoreceptors and the RPE (see Fig

However, employing different techniques can lead to varying results when comparing the bioavailability of products

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