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When all SNPs selected are valid IVs, the weighted average of Wald ratio estimates for each variant is calculated using the IVW method, which can provide the most accurate estimates (38)
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SPOP mutation drives prostate tumorigenesis in vivo through coordinate regulation of PI3K/mTOR and AR signaling
[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Bansal A., Simon M.C
Variance-stabilizing transformation (VST) was applied to the normalized data to reduce heteroscedasticity and improve interpretability for downstream statistical analyses
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