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Thus, oxidative damage of DG function may impair structural plasticity and disrupt synaptic neurotransmission [43]

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the boxed portion of the sequences indicates the CDRs (Kabat definition)

When neutrophils and macrophages get stimulated by a phagocytic stimulus, produces a respiratory burst, which is characterized by an increase in oxygen consumption, activation of the Hexose-Monophosphate (HMP) shunt and generation of Free Radicals (FR), Reactive Oxygen Species (ROS) and their metabolic products

In mouse models of depression, H3K9bhb is reduced, and KD or BHB administration exerts antidepressant effects by increasing H3K9bhb levels and BDNF expression, linking BHB and BDNF via H3K9bhb [157]

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