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Fat storage pathways become more active

| Gynecomastia can sometimes resolve on its own, particularly in adolescent boys, where it often settles within six months to two years as hormones stabilise

Ultrasound in Obstetrics & Gynecology , 48(3), 318-332

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Thus, while cellular studies indicate low toxicity and functional potential, further in vivo studies are required to assess distribution, metabolism, and clearance, as well as their long-term effects on organs and immune response (Table 3)