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While subpockets B and C are rather large, subpocket A is narrow and restricted in depth by FAD at the bottom of the pocket, limiting the choice of modifications of the inhibitor in subpocket A

Alternatively, many cancer cells may simply be unable to use the TSS pathway

[DOI] [PubMed] [PMC] Conze D, Brenner C, Kruger CL

These higher-dose protocols have not been evaluated in human clinical trials, so there is no evidence that they are more effective than standard protocols

Chemotherapeutic drugs are designed to selectively target rapidly proliferating cells, but in most neurons this process is stopped

Strategic is better