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In pigmented mammals, the eye has the highest concentration due to binding by melanin [74]
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People searching for how to permanently remove facial pigmentation from the face usually achieve better results with dermatologist-recommended treatments such as chemical peels, laser procedures, and medical skincare

For instance, in the brain, it has been described that neurons operate in a strong physical and metabolic association with astrocytes and glial cells, and the dysregulation of this cooperation contributes to the development of brain disease ( Unlike other types, human brain organoids are usually generated only from human pluripotent stem cells (both hESCs and hiPSCs), mainly due to the low regenerative capacity of the adult human brain (Tang et al., 2022)

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