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Description
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Regarding neuroinflammation, both lithium and memantine reduced IL-4 levels in the frontal cortex

A method for preventing drug-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent, wherein the therapeutic agent is an antioxidant or anti-apoptotic agent, wherein the pharmaceutical composition is administered prior to onset of therapy with the drug, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration

For instance, microenvironment changes can help identify the early influences of carcinogens in promoting tumorigenesis (81, 101, 102) and serve as biological markers of chemical exposure (103)

Curr Opin Colloid Interface Sci 39:1123
