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7 Conclusion and perspective As per Center of Disease Control and Prevention (CDC), TBI resulted in 223,000 hospitalizations and 64,300 deaths in 2020 (Peterson et al., 2022)

The gene-specific primers used for qPCR are listed in Supplementary Table 3

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We treated TC1-6 cells with serum collected from WT or GCGR-KO mice for 72 h and found that VGF and proglucagon protein levels were significantly increased in GCGR-KO serum-treated cells (Fig

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Taken together, these advancements position zebrafish as a cornerstone model in precision oncology and personalized medicine paradigms