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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Brown E.D.L., Obeng-Gyasi B., Hall J.E., Shekhar S
Nonetheless, many studies established the association of mitochondrial dysfunction with insulin resistance in various tissues [64, 113-117]
On the basis of the results available up to date, the Global Initiative for Chronic Obstructive Lung Disease [119] recognizes that mucolytic and antioxidant drugs, such as NAC, can be used as an adjunct therapy to reduce the risk of acute exacerbation of COPD, but in a limited way due to the lack of robust randomized controlled clinical trials (level of evidence B)
If sufficient endogenous and exogenous antioxidants are available, oxidative damage can be prevented
[DOI] [PubMed] [Google Scholar] Miao Y., Lv D., Wang P., Wang X.C., Chen J., Miao C
[DOI] [PubMed] [Google Scholar] 45.Yokoi T., Yoshitake H., Tatsumi T
