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You want to differentiate which one of them is causing the issue

This may be due to patients being in the early stages of ALS and not showing rapid progression, the team noted

The VEGFR2-Akt-eNOS signaling pathway was directly activated (i.e., without the need for other known ligands or shear stress), controlling vasomotor tone (both smooth muscle and endothelium), and the Src-Caveolin-1-eNOS pathway was activated [103,104]

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