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& Stamatoyannopoulos, G

PE-22-28 inhibits TREK-1 with an IC50 of 0.12 nM, as determined by electrophysiology in HEK293 cells expressing human TREK-1

The City Council asked for the audit in June 2022 to take a deep dive into the departments complaint process

Medical suppliers list it alongside saline and sterile water products

Initial response at 4 to 8 weeks

Research Highlights Phase 1 (12 weeks): Reductions between ~2.6% and ~11.3% Phase 2 (48 weeks): Lower-dose groups reached ~9% reductions Higher-dose and titration groups achieved ~20% reductions Control groups saw ~0.4% These outcomes place Eloralintide among the strongest-performing compounds within the amylin-pathway category