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This suggestion is supported by the fact that glutathione S-transferases have been shown to be associated with resistance 27 and also to protect insect tissues from the damaging effects of oxidative stress and extent life span of insects by increasing solubility and excretion of free radicals 7,44,45,46

Fenimore et al

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So PPAR activity and its effect in the different cell types needs to be investigated

These effects were again rescued by blocking NMDARs with AP5 [45], thereby confirming that ventricular NMDARs represent a promising molecular target to treat arrhythmias