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Some people with certain deficiencies such as Crohns disease and coeliac may struggle to get enough B12 in their diet. If you think youve overdosed on vitamin B12, Dr Thornber recommends you contact your GP or a hospital ASAP.

your body can still regulate GH output to some degree (for example, if IGF-1 gets too high, feedback mechanisms can reduce further GH release)

John DiBella Published: November 3, 2025 Fact-checked by Dr

Patil, H

The deficiency needs to be corrected through supplementation that bypasses the damaged absorption pathway, while the underlying gut or pancreatic condition is treated separately

When NNMT is active, it slows fat breakdown, making your body use energy less efficiently