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A return to baseline levels with amifostine treatment occurred for these pathways within a week of radiation exposure

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10.1073/pnas.0607423103 13 BeghiE.PupilloE.BonitoV.BuzziP.CaponnettoC.ChiA.et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] Spinks J

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Clinical Note: Fat Malabsorption Impairment in lipid digestion or absorption leads to fat malabsorption , which may occur due to: Bile salt deficiency Pancreatic enzyme insufficiency Intestinal mucosal damage Clinically, fat malabsorption results in steatorrhea , weight loss, and deficiencies of fat-soluble vitamins (A, D, E, and K), highlighting the medical importance of proper lipid digestion and absorption

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Because protocols differ significantly across studies, there is no universally accepted standard dose for general use outside regulated medical environments

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Indeed, FAS has been shown to interact with PMP70, an ATP binding cassette subfamily D transporter that transports fatty acyl CoA into peroxisomes (Hillebrand et al., 2012), directly linking FAS to peroxisomal lipid metabolism

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