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A return to baseline levels with amifostine treatment occurred for these pathways within a week of radiation exposure

10.1073/pnas.0607423103 13 BeghiE.PupilloE.BonitoV.BuzziP.CaponnettoC.ChiA.et al

[DOI] [PMC free article] [PubMed] [Google Scholar] Spinks J

Clinical Note: Fat Malabsorption Impairment in lipid digestion or absorption leads to fat malabsorption , which may occur due to: Bile salt deficiency Pancreatic enzyme insufficiency Intestinal mucosal damage Clinically, fat malabsorption results in steatorrhea , weight loss, and deficiencies of fat-soluble vitamins (A, D, E, and K), highlighting the medical importance of proper lipid digestion and absorption

Because protocols differ significantly across studies, there is no universally accepted standard dose for general use outside regulated medical environments

Indeed, FAS has been shown to interact with PMP70, an ATP binding cassette subfamily D transporter that transports fatty acyl CoA into peroxisomes (Hillebrand et al., 2012), directly linking FAS to peroxisomal lipid metabolism
