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Methylglyoxal induces reactive oxygen species formation The entanglement of the MGO detoxification pathway with the redox status, through affecting GSH availability and glyoxalase efficiency as explained prior, has implications for the ROS balance in BMECs exposed to MGO

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Cells were then replaced with fresh media and incubated for another 24 h

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Moreover, silibinin shows potential as an adjuvant in mitigating numerous side effects of anti-cancer therapies, such as hepatotoxicity and neurotoxicity [883, 884]

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and J.W

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10.1016/j.cell.2015.10.001 43 SiesH

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Kwon, W

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