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Furthermore, the authors results underscore that, beyond its established role in immune cell recruitment, CXCR3 within CNS glial cells exerts a pivotal role in mitigating the pro-Th17 cytokine/chemokine environment during EAE, consequently curtailing Th17 cell proliferation within the CNS and attenuating disease progression

Beyond these functions, ATM regulates peroxisome and mitochondrial function 8,9 and impacts glucose import (GLUT1 pS490) and the glycolysis/pentose phosphate pathway (PPP) switch (HSP27:G6PD), particularly in response to exogenous damage 10,11

IGF-1 LR3 enhances lean mass, supports satellite cell proliferation, and accelerates repair following physical exertion

Nature 347:386388

Aging Cell 20 , e13337 (2021)

Consequently, in the context of inhalation formulations based on nanoparticles, the nanoparticles can be modified to favor surface alterations aimed at an efficient and safe charge for the delivery of the therapeutic agent to the lungs [53,114]