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Conversely, inhibiting TLR4 can suppress microglial activation, alleviate neuroinflammation, improve cognitive function, and mitigate synaptic plasticity impairments and depression-like symptoms via this pathway (159, 160)

Two-Step Real-Time RT PCR Total RNA extraction was performed after cell collection using TRI Reagent (Molecular Research Center, Inc.) according to the manufacturers instructions
The concentration of Ru(II)-OH in nanoparticles were assessed via ICP-MS

PPI analysis using the STRING database and Cytoscape software identified Fasn as a central hub gene

Yet, when given at therapeutic doses to non-abusers, its abuse potential may be lower compared to benzodiazepines, stimulants, or opioids (Loftus and Wright, 2014)

Oncol.: Official J
