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The compound's pro-angiogenic effects improve vascular supply to connective tissue, an area limited in blood flow and repair capacity

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intermittent treatment with senolytics have conclusively reduced senescent cell burden in peripheral tissues (fat, lung, kidney, pancreas, cartilage, and muscle), improved pathologies in these tissues, and extended healthspan and lifespan (45, 46, 100-103)

Chondroclasts = osteoclasts at the chondro-osseous junction

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