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Unfortunately, several reports suggested worse outcomes including longer time for viral clearance, or elevated composite endpoint of ICU admission or even death, owing to the use of corticosteroids (Auyeung et al., n = 309), a longer time in viral clearance was observed in the corticosteroids-receiving MERS-CoV patients (Arabi et al., 2020a)

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Based on the structural characteristics of their core ATPase subunits, chromatin-remodeling complexes are classified into four main families: SWI/SNF, ISWI, CHD, and INO80/SWR1, each with distinct functional modes [49]