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This prevents premature drug degradation and allows for lower doses to be used for direct delivery to the lungs

Moreover, overexpression of genes such as glutathione reductase 1 (GSR1) and glyoxalase enzyme 1 (GLO1) has been strongly correlated with anxiety phenotypes (Hovatta et al., 2005), with GLO1 inhibitors showing potential in alleviating anxiety (Distler et al., 2012)

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This is particularly relevant for rotator cuff injuries, where the damaged structure is largely tendinous

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