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The Mayo Clinic shares that those most at risk of low levels include (5): people who dont consume enough vitamin B12 in their diet people diagnosed with pernicious anemia people whove had gastric surgeries people with intestinal issues, such as celiac or Crohns disease People following a vegetarian diet are especially at risk of deficiency

In short, mRNA vaccination following infection does generate a stronger immune response, with the timing of the prior infection (rather than its severity) largely determining post-vaccination IgG levels

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doi: 10.1016/j.jconrel.2014.10.026 [6] Zhao Z, Hu Y, Hoerle R, et al

This difference likely reflects the accumulated effect of factors involved in the epidemiologic and nutrition transition effect, as described earlier