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Fourteen of these reviewed the efficacy of vitamin B6 in reducing nausea and vomiting of pregnancy, concluding that vitamin B6 an effective treatment for mild to moderate nausea, however did not find evidence to support reduction in vomiting.[25] Thus, doses of 10-25 mg orally every 6 hours has been shown to be effective in limiting nausea symptoms, but limited efficacy in vomiting, without teratogenic effects.[23-24,26-28] Safety As for safety, Shrim et al (2009) conducted a study among 192 pregnant women, 96 of which reported taking higher than standard doses of vitamin B6 and were compared to a group of 96 women who did not report vitamin B6 use

Kageyama S, Ii H, Taniguchi K, Kubota S, Yoshida T, Isono T

The average peak signal-to-noise (S/N) ratio for GSTA4 and GAPDH calculated by the software was 194.1 35.2 and 866.5 180.4, respectively

(1998) Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels

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Trends Plant Sci 14(3):133139