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As oxidative stress continues to exacerbate damage to RTCs, the ability for phosphatidylserine (PS), situated on the cells inner side, to move outward increases and its ability to move inward decreases, resulting in PS flipping to the cell surface

AniS is part of the FNR regulon and may be responsible for the downregulation of FNR-repressed genes

The number of transcriptional regulators acting in this scenario is strongly limited but always includes the NF-B transcription factor family, prominently placed 18

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In contrast, the 6GGE-troriluzole complex showed an RMSD increase up to 50 ns, followed by a sharp decline to 60 ns, before increasing again and then stabilizing into a unique trajectory for the remainder of the simulation