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doi: 10.1038/nplants.2015.125
Theyre not shortcuts
Johnston RC, Yao K, Kaplan Z et al (2023) Epik: pKa and protonation state prediction through machine learning
Additionally, Life Extension has a rocky history with the FDA, due to the company making unsupported treatment claims (among other things)
doi: 10.1007/pl00007853
"Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder"
