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Physical responses to corticosteroid, i.e

Luger, Are melanocortin peptides future therapeutics for cutaneous wound healing?, Wiley, Feb

reported that HIF-1 and HIF-2 mRNA were overexpressed in segments of rat IVC exposed to prolonged 2-g tension and that the overexpression was reversed by the HIF inhibitor U0126 [91]

This makes the compound a cleaner tool for isolating fat-metabolism effects in experimental research where mitogenic side effects would confound results