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Contributing Factors While mites play a central role in mange development, several contributing factors can exacerbate the condition or increase susceptibility: Poor hygiene and sanitation create an environment conducive to mite infestation
An omnivorous diet allows for the B12 intake through animal products (with a bioavailability ranging from 24% to 36% in eggs, up to 65% in lean meat) (Rucker et al., 2007)
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Much larger solubility than in pure water
9 Immunosenescence is also regulated by signaling pathways such as the nuclear factor-kappa B (NF-B), mTOR, JAK-STAT, melatonin, and sirtuin pathways, whose dysregulation leads to aberrant immune responses and increased susceptibility to age-related diseases
10.1016/s0928-4257(99)00119-9 [DOI] [PubMed] [Google Scholar] Sikiric P., Mikus D., Seiwerth S., Grabarevic Z., Rucman R., Petek M., et al
