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This suggests that components involved in TJ disassembly may represent useful therapeutic targets by limiting the impact of enteric pathogens on intestinal barrier integrity and restricting their systemic spread

doi: 10.1016/j.cell.2023.09.012 [DOI] [PMC free article] [PubMed] [Google Scholar] 151.Halwani AA

Putnam FW

Key Ingredient Highlights: Glutathione A potent antioxidant that helps reduce the look of uneven skin tone and dullness, leaving skin looking more luminous

So the fair summary for BPC-157 within KLOW is: strong and interesting preclinical data, a real mechanistic rationale, and a near-total absence of the human efficacy and safety evidence that would justify confidence in the systemic claims made for it

Proteins 12, 11491160
