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Oxidative stress, along with structural changes such as axonal loss and demyelination from toxic insults like hyperglycemia and alcohol consumption, are also associated factors

Abstract Mitochondrial functionality and cellular iron homeostasis are closely intertwined

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However, the experimental results indicated that neither caffeine nor GCE alleviated hepatic steatosis, but the GCE-treated rats showed lower hepatic triglyceride levels compared with the caffeine group