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This triggers the cAMP signalling cascade, which activates protein kinase A (PKA), leading to hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) activation, resulting in triglyceride hydrolysis in adipocyte cell models

[DOI] [PubMed] [Google Scholar] 57.Japjec M., Horvat Pavlov K., Petrovic A., Staresinic M., Sebecic B., Buljan M., Vranes H., Giljanovic A., Drmic D., Japjec M., et al

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Retrieved December 8, 2023

The increased CDC confers potential advantages for therapeutic use, either alone or in combination with Daratumumab, to potentiate its effect on MM cells [93]