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Description
In white adipose tissue of obese, insulin-resistant and aged mammals, NNMT is dramatically upregulated and because it consumes both the universal methyl donor (SAM) and the NAD precursor (nicotinamide), its hyperactivity simultaneously depletes the cellular methylation reserve and the NAD-salvage pool [1,2]

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It helped with energy and my favorite part it helped with my muscle pain in my legs

[DOI] [PubMed] [Google Scholar] 11.Semalty M, Semalty A, Joshi GP, et al
