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Description
A true lipoic acid deficiency (called lipoic acid synthetase deficiency) is a rare type of neurometabolic disease

Dendritic mitochondria reach stable positions during circuit development

A systematic review and meta-analysis found no significant differences in all-cause mortality among these dosages, suggesting that doses greater than 3 g per day may not provide additional benefits [42]
In this view, nutrients, such as glucose or free fatty acids, provide intermediate metabolites the ability to interact directly with an enzyme (the metabolic sensor) that rules the rate limiting step of a metabolic process, thus regulating substrate preference

Oct 2015;102(4):943-50

Myelin damage and repair in pathologic CNS: challenges and prospects
