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Zhou N, Corsini E, Antonoff M, Hofstetter W, Mehran R, Rajaram R, Roth J, Sepesi B, Swisher S , Vaporciyan A, Walsh GL, Rice D

demonstrated that amino acids and TCA cycle intermediates were elevated in ovarian cancer tissues ( via enhancing angiogenesis, and decreased cell adherence ( via an anaplerotic reaction of the TCA cycle intermediate -ketoglutarate, which contributes to redox balance and increase NADH production for the proliferation of cancer cells ( et al

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[69] This contradiction may be due to the fact that the effect of TGF- has been shown to be highly context-dependent

Schwartz DL, Hutcheson K, Barringer D, Tucker SL, Kies M, Holsinger FC, Ang KK, Morrison WH, Rosenthal DI , Garden AS, Dong L, Lewin JS

Diabetic patients are known to have a multifactorial hypercoagulable state related to increased inflammatory markers, and increased platelet aggregation (and indeed, an increased risk for downstream clinical effects such as stroke, heart attack, and other thrombotic events)