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Rascher-Eggstein, G

N., Clayden J

The GST inhibitor, 6-(7-nitro-2, 1, 3-benzoxadiazol-4-ylthio) hexanol (NBDHEX), induced caspase activation, apoptosis, and cell death in human mesothelioma cell lines by activating c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase (MAPK) pathways (78)

Such genomic instability is accelerated and induces progressive decline with age, although organisms deploy nuclear and mitochondrial DNA repair systems (Kuilman et al., 2010

Clusters 2, 4, and 5 were identified as profibrotic lipid-associated macrophages (LAMs) because of high expression of profibrotic genes (Fn1, Spp1, CD44) and lipid metabolism genes (Lpl, Trem2, Fabp4, Fabp5)

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