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Regulation of FOXO ubiquitination by Mdm2 is likely to be direct since Mdm2 and FOXO co-immunoprecipitate

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Likewise, Wang and colleagues found that the mean postoperative sperm DNA fragmentation rate in infertile men with clinical varicocele and elevated sperm DNA fragmentation levels who underwent varicocele repair and fathered a child was lower than in those who did not conceive (13.9% 9.7% vs