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Additionally, NRC-03 and NRC-07, two AMPs from the pleurocidins AMP family, exhibited equal killing effect at a concentration of 50M on normal MCF7 cells and on paclitaxel-resistant breast cancer cell line MCF7-TX400 that possess 2.6 times of P-gp expression more than the normal MCF7 cells, achieving about 60% of cell killing rate

Images were captured using a confocal laser-scanning microscope to assess NF-B p65 nuclear translocation

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Jose S., Hughbanks M.L., Binder B.Y.K., Ingavle G.C., Leach J.K

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Thus, inhibition of inflammation also has a very important effect on wound healing, especially in the period from inflammation to proliferation