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Children aged 412 years were diagnosed with ASD according to DSM criteria, both boys and girls were included, and the study explicitly excluded participants with major psychiatric comorbidities such as ADHD, depressions, bipolar disorder, anxiety disorders, epilepsy, severe intellectual disabilities, or recent antipsychotic use, ensuring relative homogeneous sample focused on irritability

Though there is no set dosage, most evidence suggests that 300600 mg is sufficient and safe

If any of those enzymes is not working properly, porphyrins are not converted to haem and accumulate in the body instead